Anti-SLC44A4/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-SLC44A4/FITC Conjugated抗体

Anti-SLC44A4/FITC Conjugated抗体

商家询价

产品名称: Anti-SLC44A4/FITC Conjugated抗体

英文名称: Anti-SLC44A4/FITC

产品编号: YB--13961R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-SLC44A4/FITC Conjugated抗体

产品编号 YB-13961R-FITC
英文名称 Anti-SLC44A4/FITC
中文名称 FITC标记的胆碱转运体样蛋白4
别    名 Solute carrier family 44, member 4; SLC44A4; CTL4; FLJ14491; NG22; CTL4_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Horse, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 79kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC44A4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Choline is an essential nutrient that is required for the synthesis of both acetylcholine, a neurotransmitter found in cholinergic nerve terminals, and phosphatidylcholine, a key component of cell membranes. Choline deficiencies are associated with defects in cell growth and have been implicated in disorders such as Alzheimer’s and Parkinson’s disease. The choline transporter-like protein family (CTL) are solute carriers that transport choline, a compound which is not able to permeate cells, across the cell membrane. CTL4, also known as SLC44A4 (Solute carrier family 44 member 4), is a multi-pass membrane protein which can fuse with Neu1, generating a CTL4-Neu1 transcript. This fusion is implicated in sialidosis, a disease characterized by improper lysosomal storage.

Subcellular Location:
Membrane; Multi-pass membrane protein (By similarity).

DISEASE:
Note=An interstitial deletion causing the fusion of exon 10 of CTL4 with the 3'-UTR of NEU has been detected in two patients affected by sialidosis.

Similarity:
Belongs to the CTL (choline transporter-like) family.

Database links:
 

UniProtKB/Swiss-Prot: Q53GD3.2



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications