SGI-7079 (SGI7079), CAS#1239875-86-5, Axl抑制剂, AbMole品牌，中国库存。
产品名称： SGI-7079 (SGI7079), CAS#1239875-86-5, Axl抑制剂, AbMole品牌，中国库存。
英文名称： SGI-7079, SGI7079
产品编号： M2180
产品价格： 0
产品产地： 美国
品牌商标： AbMole
更新时间： null
使用范围： null
SGI-7079 is a novel Axl inhibitor. SGI-7079 decreased IBC cell proliferation, migration and invasion in vitro and inhibited tumor growth of IBC cells in vivo. Mesenchymal cells also expressed increased levels of the receptor tyrosine kinase Axl and showed a trend toward greater sensitivity to the Axl inhibitor SGI-7079, whereas the combination of SGI-7079 with erlotinib reversed erlotinib resistance in mesenchymal lines expressing Axl and in a xenograft model of mesenchymal NSCLC.