DCUN1D3,DCN1样蛋白3抗体

产品编号HZ-19307R
英文名称DCUN1D3
中文名称DCN1样蛋白3抗体
别 名44M2.4; DCN1 defective in cullin neddylation 1 domain containing 3 (S. cerevisiae); DCN1 defective in cullin neddylation 1 domain containing 3; DCN1 like protein 3; DCN1-like protein 3; DCNL3_HUMAN; DCUN1 domain containing protein 3; DCUN1 domain-containing protein 3; dcun1d3; Defective in cullin neddylation protein 1 like protein 3; Defective in cullin neddylation protein 1-like protein 3; DKFZp686O0290; FLJ41725; MGC48972.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Cow,
DCUN1D3,DCN1样蛋白3抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量34kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DCUN1D3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DCUN1D3,DCN1样蛋白3抗体PubMedPubMed
产品介绍background:
Dcun1D3 is a 304 amino acid protein that contains one Dcun1 domain. The Dcun1 domain is an approximately 190 residue module that is thought to have the features of a basic helix-loop-helix leucine zipper domain, a domain commonly found in transcription factors. It has been suggested that Dcun1D3 may be involved in cell cycle progression and cell growth. The gene that encodes Dcun1D3 maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. Chromosome 16 houses the CREBBP gene that encodes a critical CREB binding protein that is responsible for the Rubinstein-Taybi syndrome, a rare disorder characterized by mental retardation and predisposition to tumor growth and white blood cell neoplasias.

Subcellular Location:
Contains 1 DCUN1 domain.

Gene ID:
123879

Database links:
Entrez Gene: 123879 Human
Entrez Gene: 504926 Cow
Entrez Gene: 233805 Mouse
Entrez Gene: 309035 Rat
SwissProt: Q5E9V1 Cow
SwissProt: Q8IWE4 Human
SwissProt: Q8K0V2 Mouse
SwissProt: Q4V8B2 Rat
Unigene: 101007 Human
Unigene: 31539 Mouse
Unigene: 211721 Rat

DCUN1D3,DCN1样蛋白3抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.