Anti-FGFR1 (P252S) Mouse Monoclonal Antibody-抗体-抗体-生物在线

Anti-FGFR1 (P252S) Mouse Monoclonal Antibody

商家询价

产品名称： Anti-FGFR1 (P252S) Mouse Monoclonal Antibody

英文名称： Anti-FGFR1 (P252S) Mouse Monoclonal Antibody

产品编号： 26254

产品价格： null

产品产地：美国

品牌商标： NewEastBio

更新时间： null

使用范围： ELISA、WB、 IHC

武汉纽斯特生物技术有限公司

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产品详情

FGFR1 (P252S) [26254]
[100ul]

Catalog Number: 26254

Gene Symbol: FGFR1, BFGFR, CD331, CEK, FGFBR, FLG

Description: Anti-FGFR1 (P252S) Mouse Monoclonal Antibody

Background: The protein FGFR1 is highly conserved between members and throughout evolution. This particular family member of FGFR1 binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations of FGFR1 protein have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome.

Immunogen: A synthetic peptide from the internal region of FGFR1 which includes the mutation of P252S, human origin.

Applications: ELISA, WB, IHC

Recommended Dilutions:
ELISA: 1:1000-1:2000
WB: 1:500-1:1000
IHC: 1:50-1:100

Concentration: 1 mg/ml

Host: Mouse

Format: Liquid

Clonality: Monoclonal

Isotype:

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes P252S mutant, but not wild-type FGFR1 of vertebrates.

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles

Western blot:

Western blot analysis of recombinant FGFR1 (P252S) and wildtype proteins. Purified His-tagged FGFR1 (P252S) protein (22-376aa, 45KD, lane 2) and corresponding wildtype protein (lane 1) were blotted with anti-FGFR1 (P252S) monoclonal antibody (Cat. #26254).

Immunofluorescence:

Immunofluorescence of cells expressing FGFR1 proteins with anti-FGFR1 (P252S) antibody. HEK293T cells were transfected with pCDNA3-GFP-FGFR1 (P252S) plasmid , pCDNA3-GFP-FGFR1 (WT) plasmid , pCDNA3-GFP-FGFR1 (P252R) plasmid or pCDNA3-GFP-FGFR1 (P252T) plasmid, then fixed and stained with anti-FGFR1 (P252S) monoclonal antibody (Cat. #26254).