VEGF Receptor 2抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
VEGF Receptor 2抗体

VEGF Receptor 2抗体

商家询价

产品名称： VEGF Receptor 2抗体

英文名称： VEGF Receptor 2Antibody

产品编号： XY26415-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 VEGF RECEPTOR 2抗体Applications

In-house applications ELISA, IHC, WB, FC     Application not tested? Please see our Guarantee.
Species specificity Human, Mouse; other species not tested.
Images
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  • 26415-1-AP;human placenta tissuehuman placenta tissue were subjected to SDS PAGE followed by western blot with 26415-1-AP( KDR Antibody) at dilution of 1:600
  • 26415-1-AP;human oesophagus cancer tissueImmunohistochemistry of paraffin-embedded human oesophagus cancer tissue slide using 26415-1-AP( KDR Antibody) at dilution of 1:200 (under 10x lens).
  • 26415-1-AP;human oesophagus cancer tissueImmunohistochemistry of paraffin-embedded human oesophagus cancer tissue slide using 26415-1-AP( KDR Antibody) at dilution of 1:200 (under 40x lens).
  • 26415-1-AP;HUVEC cells1X10^6 HUVEC cells were stained with 0.2ug KDR antibody (26415-1-AP, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.
Positive WB detected in Human placenta tissue, mouse heart tissue
Positive IHC detected in Human oesophagus cancer tissue, human colon cancer tissue, human lung cancer tissue
Positive FC detected in HUVEC cells
Recommended dilution WB : 1:200-1:2000
IHC : 1:50-1:500
 VEGF RECEPTOR 2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information VEGF RECEPTOR 2抗体
Immunogen VEGF Receptor 2 fusion protein Ag24589 Full name Kinase insert domain receptor (a type III receptor tyrosine kinase)
Calculated molecular
weight		 1356aa,152 kDa Observed molecular 
weight		 200 kDa
GenBank accession 
number		 BC131822 Gene ID (NCBI) 3791
Gene symbol KDR Synonyms CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2
Background

KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas. VEGF RECEPTOR 2抗体

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