Synonyms : cEPO
Host : CHO cell
Sequence : The extracellular domain of human cEPO(NP_000790.2)(Pro30-Arg193)(Arg103Glu) is fused to the N-terminus of the Fc region of a mutant human IgG1.
Molecular Mass: 44KDa (monomer)
Non-lytic : Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).
Purity : >98%，by SDS-PAGE under reducing conditions
Endotoxin Content : <0.06 EU/μg as determined by LAL test.

Activity: Measured by the dose-dependant stimulation of human megakaryoblastic leukemia cells.
Formulation : Lyophilized from 0.2 μm-filtered solution in PBS.
Reconstitution : Reconstitute at 100 μg/ml in sterile PBS.
Use / Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Avoid freeze/thaw cycles.