ITGB1 monoclonal antibody, clone DF7
产品名称: ITGB1 monoclonal antibody, clone DF7
英文名称: ITGB1 monoclonal antibody, clone DF7
产品编号: MAB5274
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native ITGB1.
- Immunogen:
- Native purified human ITGB1.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody reacts with the b1 subunit of the integrin protein family. The monoclonal antibody reacts with an extracellular epitope of the b1 integrin molecule. b1 -Integrins mediate cell-extracellular matrix interactions and share a common b-subunit. Monoclonal antibodies against this b1 -Integrin subunit are applicable in paraffin-embedded and frozen sections, immunoblotting and immunoprecipitation. Numerous studies have shown that b1 -Integrins have a distinct and wide cellular distribution and that there are alterations in malignant cells in their b1-integrin expression. Monoclonal antibody to b1 integrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (1% BSA, 0.1% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Western Blot
- ELISA
- Entrez GeneID:
- 3688
- Gene Name:
- ITGB1
- Gene Alias:
- CD29,FNRB,GPIIA,MDF2,MSK12,VLA-BETA,VLAB
- Gene Description:
- integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
- Omim ID:
- 135630
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019420,OTTHUMP00000046253,OTTHUMP00000063731,OTTHUMP00000063732,OTTHUMP00000063733,fibronectin receptor beta subunit,integrin VLA-4 beta subunit,integrin beta 1
- Gene Pathway
- Arrhythmogenic right ventricular cardiomyopathy (ARVC)
- Axon guidance
- Cell adhesion molecules (CAMs)
- ECM-receptor interaction
- Focal adhesion
- Hypertrophic cardiomyopathy (HCM)
- Leukocyte transendothelial migration
- Pathogenic Escherichia coli infection - EHEC
- Pathways in cancer
- Regulation of actin cytoskeleton
- Small cell lung cancer