HIF1A monoclonal antibody, clone OZ12
产品名称： HIF1A monoclonal antibody, clone OZ12
英文名称： HIF1A monoclonal antibody, clone OZ12
产品编号： MAB1893
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant HIF1A.
- Immunogen:
- Recombinant protein corresponding to amino acids 530-826 of human HIF1A.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.08% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- Immunoprecipitation (2 ug/mg)
Gel Supershift Assay (1 mg/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Effects of antioxidant vitamins on renal and hepatic erythropoietin production.
Jelkmann W, Pagel H, Hellwig T, Fandrey J.Kidney Int. 1997 Feb;51(2):497-501.
- 2.
- Oxygen- and dioxin-regulated gene expression in mouse hepatoma cells.
Gassmann M, Kvietikova I, Rolfs A, Wenger RH.Kidney Int. 1997 Feb;51(2):567-74.
- 3.
- Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors.
Huang LE, Ho V, Arany Z, Krainc D, Galson D, Tendler D, Livingston DM, Bunn HF.Kidney Int. 1997 Feb;51(2):548-52.
- Application Image
- Immunofluorescence
- Immunoprecipitation
- Gel Supershift Assay
- Entrez GeneID:
- 3091
- Gene Name:
- HIF1A
- Gene Alias:
- HIF-1alpha,HIF1,HIF1-ALPHA,MOP1,PASD8,bHLHe78
- Gene Description:
- hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- Omim ID:
- 603348
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- ARNT interacting protein,hypoxia-inducible factor 1, alpha subunit,hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor),member of PAS superfamily 1
- Related Disease
- Acute Disease
- Adenocarcinoma
- Altitude Sickness
- Angina Pectoris
- Anoxia
- Breast cancer
- Breast Neoplasms
- Carcinoma, Hepatocellular
- Carcinoma, Intraductal, Noninfiltrating
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Renal Cell
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Cardiovascular Diseases
- Cellulitis
- Cleft Lip
- Cleft Palate
- Colorectal Neoplasms
- Coronary Disease