TSPEAR,早期未分化视网膜及晶状体蛋白EURL抗体

产品编号HZ-9577R
英文名称TSPEAR
中文名称早期未分化视网膜及晶状体蛋白EURL抗体
别 名C21orf14; C21orf38; C21orf7; Chromosome 21 open reading frame 38; Chromosome 21 open reading frame 91; Early undifferentiated retina and lens; EURL; Protein EURL homolog; YG81; TSEAR_HUMAN.
说 明 书0.1ml 0.2ml
研究领域神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse,
TSPEAR,早期未分化视网膜及晶状体蛋白EURL抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量72kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human TSPEAR/C21orf9
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
TSPEAR,早期未分化视网膜及晶状体蛋白EURL抗体PubMedPubMed
产品介绍background:
TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis.

Function:
C21orf91 belongs to the EURL family. There are three named isoforms. The exact function of C21orf91 remains unknown.

Subcellular Location:
Secreted.

Similarity:
Contains 7 EAR repeats.
Contains 1 laminin G-like domain.

Database links:
Entrez Gene: 54149 Human
Entrez Gene: 67102 Mouse
Entrez Gene: 360692 Rat
SwissProt: Q9NYK6 Human
SwissProt: Q9D7G4 Mouse

TSPEAR,早期未分化视网膜及晶状体蛋白EURL抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.