CX3CR1 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
CX3CR1 抗体

CX3CR1 抗体

商家询价

产品名称： CX3CR1 抗体

英文名称： CX3CR1 Antibody

产品编号： XY13885-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 CX3CR1 抗体

Applications
In-house applications ELISA, WB, IHC, FC, IP     Application not tested? Please see our Guarantee.
Published applications IHC, WB Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Rat
Images
Prev12NextView more validation data
  • 13885-1-AP;HL-60 cellsHL-60 cells were subjected to SDS PAGE followed by western blot with 13885-1-AP(CX3CR1 antibody) at dilution of 1:800
  • 13885-1-AP;human tonsillitis tissueImmunohistochemical of paraffin-embedded human tonsillitis using 13885-1-AP(CX3CR1 antibody) at dilution of 1:50 (under 10x lens)
  • 13885-1-AP;human tonsillitis tissueImmunohistochemical of paraffin-embedded human tonsillitis using 13885-1-AP(CX3CR1 antibody) at dilution of 1:50 (under 40x lens)
  • 13885-1-AP;SH-SY5Y cellsIP Result of anti-CX3CR1 (IP:13885-1-AP, 4ug; Detection:13885-1-AP 1:1000) with SH-SY5Y cells lysate 1600ug.
  • 13885-1-AP;K-562 cells1X10^6 K-562 cells were stained with 0.2ug CX3CR1 antibody (13885-1-AP, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.
Positive WB detected in HL-60 cells, K-562 cells, SH-SY5Y cells, U-937 cells
Positive IP detected in SH-SY5Y cells
Positive IHC detected in Human tonsillitis tissue
Positive FC detected in K-562 cells
Recommended dilution WB : 1:200-1:2000
IP : 1:500-1:5000
IHC : 1:20-1:200
 CX3CR1 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen CX3CR1 fusion protein ag4149 Full name Chemokine (C-X3-C motif) receptor 1
Calculated molecular
weight		 40 kDa Observed molecular 
weight		 47 kDa
GenBank accession 
number		 BC028078 Gene ID (NCBI) 1524
Gene symbol CX3CR1 Synonyms Beta chemokine receptor like 1, C X3 C CKR 1, CCRL1, CMK BRL 1, CMK BRL1, CMKBRL1, CMKDR1, CX3C chemokine receptor 1, CX3CR1, Fractalkine receptor, G protein coupled receptor 13, GPR13, GPRV28, V28
Background CX3CR1 抗体

CX3CR1, also known as GPR13, V28 and fractalkine receptor, belongs to the 7-transmembrane G protein-coupled receptor (GPCR) family. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12). CX3CR1 抗体

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