HYOU1 purified MaxPab mouse polyclonal antibody (B01P)
产品名称： HYOU1 purified MaxPab mouse polyclonal antibody (B01P)
英文名称： HYOU1 purified MaxPab mouse polyclonal antibody (B01P)
产品编号： H00010525-B01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human HYOU1 protein.
- Immunogen:
- HYOU1 (AAH72436.1, 1 a.a. ~ 678 a.a) full-length human protein.
- Sequence:
- MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSVCRASVTRFGF
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- HYOU1 MaxPab polyclonal antibody. Western Blot analysis of HYOU1 expression in human liver.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of HYOU1 expression in transfected 293T cell line (H00010525-T01) by HYOU1 MaxPab polyclonal antibody.
Lane 1: HYOU1 transfected lysate(74.58 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 10525
- GeneBank Accession#:
- BC072436.1
- Protein Accession#:
- AAH72436.1
- Gene Name:
- HYOU1
- Gene Alias:
- DKFZp686N08236,FLJ94899,FLJ97572,Grp170,HSP12A,ORP150
- Gene Description:
- hypoxia up-regulated 1
- Omim ID:
- 601746
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. [provided by RefSeq
- Other Designations:
- 150 kDa oxygen-regulated protein,glucose-regulated protein 170,oxygen regulated protein (150kD)
- Related Disease