Synonyms : Transforming Growth Factor beta-1; TGFB1; TGFB
Host : CHO cell
Sequence : The extracellular domain of a mutant human TGFβ1 is fused to the N-terminus of the Fc portion of human IgG4. Site-directed mutagenesis was used to change three cysteine codons into a serine codon that are located in the pro region of the TGF-β precursor at amino acid positions 33, 223, and 225.
Molecular Mass : 70 KDa (monomer)
Purity : >98%，by SDS-PAGE under reducing conditions.
Endotoxin Content : <0.06 EU/μg as determined by LAL test.

Activity : Acts in conjunction with rapamycin to inhibit T cell proliferation and induce the denovo generation of Foxp3+ Treg in the periphery, and inhibiting IL6-mediated Th17 cell differentiation.
Formulation : Lyophilized from 0.2μm-filtered solution in PBS.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Use / Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Avoid freeze/thaw cycles.