MTUS1 monoclonal antibody (M01), clone 1C7
产品名称： MTUS1 monoclonal antibody (M01), clone 1C7
英文名称： MTUS1 monoclonal antibody (M01), clone 1C7
产品编号： H00057509-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant MTUS1.
- Immunogen:
- MTUS1 (AAH33842, 1 a.a. ~ 240 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MQLQEQFDNLNAAHETSKLEIEASHSEKLELLTKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMGKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTEQAVLQESLEKESKVNKRLSMENEELLWKLHNGDLCSPKRSPTSSAIPLQSPRNSGSFPSPSISPR
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (52.14 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Down-regulation of tumor suppressor MTUS1/ATIP is associated with enhanced proliferation, poor differentiation and poor prognosis in oral tongue squamous cell carcinoma.
Ding X, Zhang N, Cai Y, Li S, Zheng C, Jin Y, Yu T, Wang A, Zhou X.Mol Oncol. 2011 Nov 18.
- 2.
- LOH and copy neutral LOH (cnLOH) act as alternative mechanism in sporadic colorectal cancers with chromosomal and microsatellite instability.
Melcher R, Hartmann E, Zopf W, Herterich S, Wilke P, Muller L, Rosler E, Kudlich T, Al-Taie O, Rosenwald A, Katzenberger T, Scholtka B, Seibold S, Rogoll D, Scheppach W, Scheurlen M, Luhrs H.Carcinogenesis. 2011 Apr;32(4):636-42. Epub 2011 Feb 4.
- 3.
- 8p22 MTUS1 Gene Product ATIP3 Is a Novel Anti-Mitotic Protein Underexpressed in Invasive Breast Carcinoma of Poor Prognosis.
Rodrigues-Ferreira S, Di Tommaso A, Dimitrov A, Cazaubon S, Gruel N, Colasson H, Nicolas A, Chaverot N, Molinie V, Reyal F, Sigal-Zafrani B, Terris B, Delattre O, Radvanyi F, Perez F, Vincent-Salomon A, Nahmias C.PLoS One. 2009 Oct 1;4(10):e7239.
- Applications
- Western Blot (Tissue lysate)
- MTUS1 monoclonal antibody (M01), clone 1C7. Western Blot analysis of MTUS1 expression in human colon.
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged MTUS1 is approximately 0.3ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 57509
- GeneBank Accession#:
- BC033842
- Protein Accession#:
- AAH33842
- Gene Name:
- MTUS1
- Gene Alias:
- ATIP,DKFZp586D1519,DKFZp686F20243,FLJ14295,KIAA1288,MP44,MTSG1
- Gene Description:
- mitochondrial tumor suppressor 1
- Omim ID:
- 609589
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq
- Other Designations:
- AT2 receptor-interacting protein,erythroid differentiation-related,mitochondrial tumor suppressor gene 1,transcription factor MTSG1