Product Introduction
Bioactivity


英文名: NCB-0846

描述: NCB-0846 是一种具有口服活性的TNIK 抑制剂(IC50:21 nM)。

体内活性: Sixty normal male and female volunteers between 18 and 40 years of age were recruited for a double-masked, placebo-controlled, crossover study in which each eye of each subject was dilated with 2.5% phenylephrine. After one hour, one eye was treated with 0.5% dapiprazole, and the contralateral eye was treated with placebo.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (133.18 mM)


关键字: Wnt | MAPK Kinase Kinase Kinase | Inhibitor | inhibit | MAP4K | NCB0846 | NCB-0846

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