ARSH,芳香基硫酸酯酶H抗体

产品编号HZ-9101R
英文名称ARSH
中文名称芳香基硫酸酯酶H抗体
别 名Arylsulfatase H; ASH; ARSH_HUMAN.
规格价格0.1ml/980元 购买 0.2ml/1580元 购买
说 明 书0.1ml 0.2ml
研究领域心血管 细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
ARSH,芳香基硫酸酯酶H抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量62kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ARSH
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ARSH,芳香基硫酸酯酶H抗体PubMedPubMed
产品介绍background:
Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling and degradation of macromolecules. Arylsulfatase H, also known as ARSH, is a 562 amino acid protein that belongs to the sulfatase family of bone and cartilage matrix proteins. Localized to the plasma membrane, Arylsulfatase H uses calcium as a cofactor to hydrolyze sulfate esters. The gene encoding Arylsulfatase D maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.

Function:

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).

Tissue Specificity:

Post-translational modifications:
The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity (By similarity).

DISEASE:

Similarity:
Belongs to the sulfatase family.

Gene ID:
347527

ARSH,芳香基硫酸酯酶H抗体Database links:
Entrez Gene: 347527 Human
Omim: 300586 Human
SwissProt: Q32KH8 Dog
SwissProt: Q5FYA8 Human
Unigene: 351533 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.