FITC标记的胱抑素S/半胱氨酸蛋白酶抑制剂S抗体
产品名称： FITC标记的胱抑素S/半胱氨酸蛋白酶抑制剂S抗体
英文名称： Anti-Cystatin S/FITC
产品编号： HZ-9218R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-Cystatin S/FITC Conjugated antibody
FITC标记的胱抑素S/半胱氨酸蛋白酶抑制剂S抗体
| 产品编号 | bs-9218R-FITC |
| 英文名称 | Anti-Cystatin S/FITC |
| 中文名称 | FITC标记的胱抑素S/半胱氨酸蛋白酶抑制剂S抗体 |
| 别 名 | Cst4; Cystatin 4; Cystatin S precursor; Cystatin SA III; Cystatin-4; Cystatin-S; Cystatin-SA-III; CYTS_HUMAN; MGC71923; Salivary acidic protein 1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 16kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Cystatin S |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function. [provided by RefSeq, Jul2008]. Function: This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively. Subcellular Location: Secreted. Tissue Specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid. Post-translational modifications: Phosphorylated at both its N- and C-terminal regions. Similarity: Belongs to the cystatin family. Database links: Entrez Gene: 1472 Human Omim: 123857 Human SwissProt: P01036 Human Unigene: 654549 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
半胱氨酸蛋白酶抑制剂超家族包含含有多种半胱氨酸蛋白酶抑制剂序列的蛋白质。有些成员是活性半胱氨酸蛋白酶抑制剂，而另一些则失去或可能从未获得这种抑制活性。超家族中有三个抑制性家族，包括1型半胱氨酸蛋白酶抑制剂（Syfin）、2型半胱氨酸蛋白酶抑制剂和激肽原。2型半胱氨酸蛋白酶抑制剂蛋白是一类半胱氨酸蛋白酶抑制剂，存在于多种人类体液和分泌物中。20号染色体上的半胱氨酸蛋白酶抑制剂基因座包含2型半胱氨酸蛋白酶抑制剂基因和假基因的大部分。该基因位于半胱氨酸蛋白酶抑制剂位点，编码2型半胱氨酸半胱氨酸肽酶抑制剂。该蛋白是一种S型半胱氨酸蛋白酶抑制剂，基于唾液、眼泪和精浆的高表达。在这些流体中的具体作用尚不清楚，但存在抗菌和抗病毒活性，与保护功能一致。[ RefSeq，Jul2008 ]提供。