Human Growth Factors & Cytokines
Recombinant Human gAcrp30/Adipolean Variant





 





		Synonyms :
apm-1 variant



		Description :
The gAcrp30 variant is a naturally occurring globular protein, obtained by proteolytic processing of adiponectin.  Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein.  Like Adiponectin, Acrp30 is capable of decreasing hyperglycemia and reversing insulin resistance.  Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids (FFAs).  The signaling receptors for adiponectin and gAcrp30 have recently been identified and names AdipoR1 and AdipoR2.  AdipoR2 is predominantly expressed in the liver.  This naturally occurring variant of human gAcrp30/Adipolean is an 18.1 kDa protein, containing 14 amino acids extra at the N-terminus of human gAcrp30/Adipolean.



		Catalog #:
450-20



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by a cytotoxicity assay using M1 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.


Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
PGAEGPRGFP GIQGRKGEPG EGAYVYRSAF SVGLETYVTI PNMPIRFTKI FYNQQNHYDG STGKFHCNIP GLYYFAYHIT VYMKDVKVSL FKKDKAMLFT YDQYQENNVD QASGSVLLHL EVGDQVWLQV YGEGERNGLY ADNDNDSTFT GFLLYHDTN 


Country of Origin :
USA
















        Size A
5μg
$80 
 


 



        Size B
25μg
$195 
 


 



        Size C
1mg
$3000 
 


 















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                    Sizes: 
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Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.