FITC标记的紧密连接蛋白5抗体
产品名称： FITC标记的紧密连接蛋白5抗体
英文名称： Anti-Claudin 5/FITC
产品编号： HZ-10296R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： Flow-Cyt=1:50-200
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Rabbit Anti-Claudin 5/FITC Conjugated antibody
FITC标记的紧密连接蛋白5抗体
| 英文名称 | Anti-Claudin 5/FITC |
| 中文名称 | FITC标记的紧密连接蛋白5抗体 |
| 别 名 | AWAL; BEC 1; BEC1; Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); Claudin5; Claudin-5;CLDN 5; CLDN5; CPETR L1; CPETRL 1; CPETRL1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; Transmembrane protein deleted in velocardiofacial syndrome; Androgen withdrawal and apoptosis induced protein RVP1 like; CLD5_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 信号转导 细胞粘附分子 细胞骨架 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | Flow-Cyt=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 23kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Claudin 5 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008] Function: Plays a major role in tight junction-specific obliteration of the intercellular space. Subunit: Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ. Subcellular Location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in activated, but not resting, CD4+ T-cells and activated monocytes. Similarity: Belongs to the claudin family. Database links: Entrez Gene: 7122 Human Entrez Gene: 12741 Mouse Omim: 602101 Human SwissProt: Q2HJ22 Cow SwissProt: O00501 Human SwissProt: O54942 Mouse Unigene: 505337 Human Unigene: 22768 Mouse
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码Caldin家族的一个成员。紧密连接蛋白是紧密连接链的完整膜蛋白和组成部分。紧密的结合链起到物理屏障的作用，以防止溶质和水自由地通过上皮或内皮细胞片之间的细胞旁空间。该基因的突变已发现在患者的心脏扑面综合症。另一种剪接转录变体编码相同的蛋白质已经发现这个基因。[ RefSeq，Aug 2008提供]