GJB6 (Human) Recombinant Protein (Q01)
产品名称: GJB6 (Human) Recombinant Protein (Q01)
英文名称: GJB6 (Human) Recombinant Protein (Q01)
产品编号: H00010804-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human GJB6 partial ORF ( AAH38934, 45 a.a. - 75 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- GDEQEDFVCNTLQPGCKNVCYDHFFPVSHIR
- Theoretical MW (kDa):
- 29.15
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 10804
- GeneBank Accession#:
- BC038934
- Protein Accession#:
- AAH38934
- Gene Name:
- GJB6
- Gene Alias:
- CX30,DFNA3,ED2,EDH,HED
- Gene Description:
- gap junction protein, beta 6, 30kDa
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq
- Other Designations:
- OTTHUMP00000018096,OTTHUMP00000176870,OTTHUMP00000176871,OTTHUMP00000176872,connexin 30,ectodermal dysplasia 2, hidrotic (Clouston syndrome),gap junction protein, beta 6,gap junction protein, beta 6 (connexin 30)
- Related Disease
- Auditory Perception
- Cholesteatoma
- Chronic Disease
- Cytomegalovirus Infections
- Deafness
- Deafness
- Disease Progression
- Genetic Predisposition to Disease
- Hearing Loss
- Hearing Loss, High-Frequency
- Hearing Loss, Noise-Induced
- Hearing Loss, Sensorineural
- Presbycusis
- Rhinitis
- Sinusitis
- Speech Perception
- Syndrome
- Usher Syndromes
- Vestibulocochlear Nerve Diseases