FITC标记的亲环蛋白(亲环素)40抗体
产品名称: FITC标记的亲环蛋白(亲环素)40抗体
英文名称: Anti-Cyclophilin 40/PPID/FITC
产品编号: HZ-9878R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-Cyclophilin 40/PPID/FITC Conjugated antibody
FITC标记的亲环蛋白(亲环素)40抗体
产品编号 | bs-9878R-FITC |
英文名称 | Anti-Cyclophilin 40/PPID/FITC |
中文名称 | FITC标记的亲环蛋白(亲环素)40抗体 |
别 名 | 40 kDa peptidyl prolyl cis trans isomerase; 40 kDa peptidyl prolyl cis trans isomerase D; 40 kDa peptidyl-prolyl cis-trans isomerase; Cyclophilin D; Cyclophilin D; Cyclophilin related protein; Cyclophilin-40; Cyclophilin-related protein; Cyclophilin40; CyclophilinD; CYP 40; CYP 40; CYP-40; CYP40; CYP40; CYPD; CYPD; MGC33096; Peptidyl Prolyl Isomerase D; Peptidyl Prolyl Isomerase D; Peptidyl-prolyl cis-trans isomerase D; Peptidylprolyl isomerase D; PPIase; PPIase D; PPID; PPID; PPID_HUMAN; Rotamase; Rotamase D. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 转录调节因子 转运蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Sheep, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 20, 40kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from hu Cyclophilin D |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of cyclosporin A (CsA) and is encoded by a single unique gene conserved from yeast to humans. Cyclophilin B (CyPB) is secreted in biological fluids such as blood or milk and binds to a specific receptor present on the human lymphoblastic cell line Jurkat and on human peripheral blood lymphocytes. Cyclophilin D (CyP40) is a widely expressed cytoplasmic protein that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. It is a widely expressed cytoplasmic protein. Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Subunit: Binds ESR1. Subcellular Location: Cytoplasm. Tissue Specificity: Widely expressed. Similarity: Belongs to the cyclophilin-type PPIase family. PPIase D subfamily. Contains 1 PPIase cyclophilin-type domain. Contains 3 TPR repeats. Database links: Entrez Gene: 5481 Human Entrez Gene: 67738 Mouse Entrez Gene: 361967 Rat Omim: 601753 Human SwissProt: Q08752 Human SwissProt: Q9CR16 Mouse SwissProt: Q6DGG0 Rat Unigene: 183958 Human Unigene: 295252 Mouse Unigene: 136915 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
亲环素是一种保守的、普遍存在的、丰富的胞浆肽脯氨酰顺反异构酶,加速了XaAPro肽键的异构化和蛋白质的复性。人亲环素A(CyPA)是165种氨基酸的胞内蛋白,是环孢菌素A(CsA)的靶标,编码的是由酵母保存到人类的单一独特基因。Cyclophilin B(CYPB)在血液或乳汁等生物流体中分泌,结合到人淋巴母细胞株Jurkat和人外周血淋巴细胞上存在的特异性受体。亲环素D(CYP40)是一种广泛表达的胞质蛋白,催化寡肽中脯氨酸-酰亚胺肽键顺式反式异构化。它是一种广泛表达的细胞质蛋白。