MMP9 monoclonal antibody, clone SB15c
产品名称： MMP9 monoclonal antibody, clone SB15c
英文名称： MMP9 monoclonal antibody, clone SB15c
产品编号： MAB3332
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant MMP9.
- Immunogen:
- Recombinant protein corresponding to human MMP9.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- human MMP-9, Does not cross react to human MMP-1, MMP-2 or MMP-3.
- Form:
- Liquid
- Isotype:
- IgG2a
- Storage Buffer:
- In 100 mM BBS, pH 8.2
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- ELISA (1:3000-1:8000)
Immunohistochemistry (2 ug/mL)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Matrix metalloproteinase 9 protects mice from anti-glomerular basement membrane nephritis through its fibrinolytic activity.
Lelongt B, Bengatta S, Delauche M, Lund LR, Werb Z, Ronco PM.J Exp Med. 2001 Apr 2;193(7):793-802.
- 2.
- Fibrillin degradation by matrix metalloproteinases: implications for connective tissue remodelling.
Ashworth JL, Murphy G, Rock MJ, Sherratt MJ, Shapiro SD, Shuttleworth CA, Kielty CM.Biochem J. 1999 May 15;340 ( Pt 1):171-81.
- 3.
- Degradation of interleukin 1beta by matrix metalloproteinases.
Ito A, Mukaiyama A, Itoh Y, Nagase H, Thogersen IB, Enghild JJ, Sasaguri Y, Mori Y.J Biol Chem. 1996 Jun 21;271(25):14657-60.
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Immunohistochemistry (Frozen sections)
- ELISA
- Entrez GeneID:
- 4318
- Gene Name:
- MMP9
- Gene Alias:
- CLG4B,GELB,MMP-9
- Gene Description:
- matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
- Omim ID:
- 120361
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq
- Other Designations:
- 92kD type IV collagenase,OTTHUMP00000031674,gelatinase B,macrophage gelatinase,matrix metalloproteinase 9,matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase),matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kD
- Related Disease
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Adenocarcinoma
- Airway Remodeling
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Aneurysm, Dissecting
- Angina Pectoris
- Angina, Unstable
- Aortic Aneurysm
- Aortic Aneurysm, Abdominal
- Aortic Aneurysm, Thoracic
- Arteriosclerosis
- Arthritis, Rheumatoid
- Asthma
- Asthma