FITC标记的高尔基体膜相关蛋白6抗体
产品名称： FITC标记的高尔基体膜相关蛋白6抗体
英文名称： Anti-GOLGA6/FITC
产品编号： HZ-13482R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-GOLGA6/FITC Conjugated antibody
FITC标记的高尔基体膜相关蛋白6抗体
| 英文名称 | Anti-GOLGA6/FITC |
| 中文名称 | FITC标记的高尔基体膜相关蛋白6抗体 |
| 别 名 | GLP; GOG6A_HUMAN; GOLGA; GOLGA6; GOLGA6A; Golgi autoantigen golgin subfamily a 6; golgi autoantigen golgin subfamily a member 6; golgin like protein; Golgin linked to PML; Golgin subfamily A member 6A; Golgin-like protein; HGNC:13567. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 信号转导 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 80kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GOLGA6 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The protein encoded by this gene is a member of the golgin family of proteins, whose members localize to the Golgi. This gene is found in a large, low copy repeat sequence or duplicon that is found in multiple copies, that are greather than 90% similar, on chromosome 15. Duplicons are associated with deletions, inversions and other chromosome rearrangements that underlie genomic disease. The protein encoded by this gene is thought to be a functional golgin protein while the majority of the related copies of this gene are thought to be transcribed pseudogenes. Tissue Specificity: Highly expressed in seminiferous tubes in testis. Highly expressed in spermatids, barely detectable in late pachytene spermatocytes, and not detectable in spermatogonia. Detected at intermediate levels in pancreas and lymph nodes, and at much lower levels in spleen, peripheral blood leukocytes, skeletal muscle, liver, lung, placenta, brain and heart. Similarity: Belongs to the GOLGA6 family. Database links: UniProtKB/Swiss-Prot: Q9NYA3.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
高尔基体参与蛋白质和脂质的分泌途径的糖基化和转运，由一系列堆叠的池体（扁平的膜囊）组成。高尔基体与微管之间的相互作用被认为是高尔基体在有丝分裂过程中碎片后重组的重要因素。由该基因编码的蛋白质是golgin家族蛋白的成员，其成员定位于高尔基体。该基因在15号染色体上的一个大的、低拷贝的重复序列或重复序列中发现，在多个拷贝中发现，相似度大于90%。复制子与基因组疾病的缺失、反转和其他染色体重排有关。该基因编码的蛋白被认为是一种功能性的高尔金蛋白，而该基因的大部分相关拷贝被认为是转录的假基因。