DES polyclonal antibody
产品名称： DES polyclonal antibody
英文名称： DES polyclonal antibody
产品编号： PAB12678
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of DES.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding T76/T77 of human DES.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 55
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody recognizes ~55 KDa of human DES without phosphorylated Thr76/Thr77. It does not recognize phosphorylated peptides confirmed by dot blot.
- Form:
- Liquid
- Storage Buffer:
- In TBS, pH 7.2 (10% Proclin300)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (0.1-1 ug/mL)
ELISA (0.01-0.1 ug/mL)
Immunoprecipitation (2-5 ug/mL)
Immunohistochemistry (2-5 ug/mL)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Protein kinase C-mediated desmin phosphorylation is related to myofibril disarray in cardiomyopathic hamster heart.
Huang X, Li J, Foster D, Lemanski SL, Dube DK, Zhang C, Lemanski LF.Exp Biol Med (Maywood). 2002 Dec;227(11):1039-46.
- 2.
- Protein kinase C phosphorylation of desmin at four serine residues within the non-alpha-helical head domain.
Kitamura S, Ando S, Shibata M, Tanabe K, Sato C, Inagaki M.J Biol Chem. 1989 Apr 5;264(10):5674-8.
- Application Image
- Western Blot
- Immunohistochemistry
- Immunoprecipitation
- ELISA
- Entrez GeneID:
- 1674
- Gene Name:
- DES
- Gene Alias:
- CMD1I,CSM1,CSM2,FLJ12025,FLJ39719,FLJ41013,FLJ41793
- Gene Description:
- desmin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq
- Other Designations:
- OTTHUMP00000064865,intermediate filament protein