NPHP5,IQCB1 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
NPHP5,IQCB1 抗体

NPHP5,IQCB1 抗体

商家询价

产品名称: NPHP5,IQCB1 抗体

英文名称: NPHP5,IQCB1 Antibody

产品编号: XY 15747-1-

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 NPHP5,IQCB1 抗体Applications

In-house applications ELISA, IF     Application not tested? Please see our Guarantee.
Published applications IF Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human
Images
Prev1NextView more validation data
  • 15747-1-AP;hTERT-RPE1 cellsIF Result of anti-NPHP5 (15747-1-AP) show the base of cilia in human hTERT-RPE1 cells by Dr. Moshe Kim.
  • 15747-1-AP;hTERT-RPE1 cellsIF Result of anti-NPHP5 (15747-1-AP,1:50) show 'focal adhesion-like' structures in human hTERT-RPE1 cells by Dr. Moshe Kim. 1% PFA fixation.
Positive IF detected in HTERT-RPE1 cells
Recommended dilution IF : 1:10-1:100
 NPHP5,IQCB1 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen NPHP5,IQCB1 fusion protein ag8203 Full name IQ motif containing B1
Calculated molecular
weight
598aa,69 kDa Observed molecular 
weight
 
GenBank accession 
number
BC005806 Gene ID (NCBI) 9657
Gene symbol IQCB1 Synonyms IQ motif containing B1, IQCB1, KIAA0036, Nephrocystin 5, NPHP5, PIQ, SLSN5
Background NPHP5,IQCB1 抗体

IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation. NPHP5,IQCB1 抗体

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