TP53BP1 polyclonal antibody
产品名称： TP53BP1 polyclonal antibody
英文名称： TP53BP1 polyclonal antibody
产品编号： PAB12507
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against partial recombinant TP53BP1.
- Immunogen:
- Recombinant protein corresponding to human TP53BP1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Specificity:
- This antibody is specific to human 53BP1 protein.
- Form:
- Liquid
- Storage Buffer:
- In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- Immunocytochemistry (1:200-1:1000)
Immunofluorescence (1:50-1:200)
Western Blot (1:2000-1:10000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- HPV-16 E7 reveals a link between DNA replication stress, fanconi anemia D2 protein, and alternative lengthening of telomere-associated promyelocytic leukemia bodies.
Spardy N, Duensing A, Hoskins EE, Wells SI, Duensing S.Cancer Res. 2008 Dec 1;68(23):9954-63.
- 2.
- Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways.
Solier S, Sordet O, Kohn KW, Pommier Y.Mol Cell Biol. 2009 Jan;29(1):68-82. Epub 2008 Oct 27.
- 3.
- Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1 alpha-deficient mouse embryonic fibroblasts.
Wirthner R, Wrann S, Balamurugan K, Wenger RH, Stiehl DP.Carcinogenesis. 2008 Dec;29(12):2306-16. Epub 2008 Oct 8.
- 4.
- Leukocyte DNA damage after multi-detector row CT: a quantitative biomarker of low-level radiation exposure.
Rothkamm K, Balroop S, Shekhdar J, Fernie P, Goh V.Radiology. 2007 Jan;242(1):244-51.
- Entrez GeneID:
- 7158
- Protein Accession#:
- NP_005648.1
- Gene Name:
- TP53BP1
- Gene Alias:
- 53BP1,FLJ41424,MGC138366,p202
- Gene Description:
- tumor protein p53 binding protein 1
- Omim ID:
- 605230
- Gene Ontology:
- Hyperlink
- Other Designations:
- tumor protein 53-binding protein, 1,tumor protein p53-binding protein, 1
- Related Disease
- Adenocarcinoma
- Ataxia telangiectasia
- Breast cancer
- Breast Neoplasms
- Carcinoma, Basal Cell
- Carcinoma, Squamous Cell
- Colorectal Neoplasms
- DNA Damage
- Esophageal Neoplasms
- Gastroesophageal Reflux
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Lung Neoplasms
- Neoplasms
- Pancreatic Neoplasms
- Skin Neoplasms
- Stomach Neoplasms
- Tobacco Use Disorder
- Werner syndrome