KIF5B/RET DY Translocation FISH Probe
产品名称： KIF5B/RET DY Translocation FISH Probe
英文名称： KIF5B/RET DY Translocation FISH Probe
产品编号： FT0007
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Labeled FISH probes for identification of gene translocation using Fluorescent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Note:
- Hybridization position of the probes on the chromosome:
-
- Probe 1:
Size:
Fluorophore:
Location: - KIF5B
Approximately 1370kb
FITC
10p11.2
- Probe 2:
Size:
Fluorophore:
Location: - RET
Approximately 1180kb
Texas Red
10q11.2
- Probe Gap:
- The gap between two probes is approximately 10,000 kb.
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Human lung adenosquamous cell carcinoma (FFPE) stained with KIF5B/RET DY Translocation FISH Probe . Human lung adenosquamous cell carcinoma showed KIF5B/RET DY translocation.
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 3799
- Gene Name:
- KIF5B
- Gene Alias:
- KINH,KNS,KNS1,UKHC
- Gene Description:
- kinesin family member 5B
- Omim ID:
- 602809
- Gene Ontology:
- Hyperlink
- Other Designations:
- kinesin 1 (110-120kD),kinesin heavy chain
- Entrez GeneID:
- 5979
- Gene Name:
- RET
- Gene Alias:
- CDHF12,HSCR1,MEN2A,MEN2B,MTC1,PTC,RET-ELE1,RET51
- Gene Description:
- ret proto-oncogene
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq
- Other Designations:
- RET transforming sequence,cadherin family member 12,hydroxyaryl-protein kinase,oncogene RET,receptor tyrosine kinase,ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)