EPHX2 Pre-design Chimera RNAi
产品名称： EPHX2 Pre-design Chimera RNAi
英文名称： EPHX2 Pre-design Chimera RNAi
产品编号： H00002053-R01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Homo sapiens epoxide hydrolase 2, cytoplasmic (EPHX2), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_001979
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 2053
- Gene Name:
- EPHX2
- Gene Alias:
- CEH,SEH
- Gene Description:
- epoxide hydrolase 2, cytoplasmic
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
- Other Designations:
- epoxide hydratase,epoxide hydrolase 2, cytosolic,epoxide hydrolase, soluble
- Related Disease
- Asthma
- Asthma
- Atherosclerosis
- Brain Ischemia
- Calcinosis
- Cardiovascular Diseases
- Carotid Artery Diseases
- Cerebrovascular Accident
- Chronic Disease
- Colorectal Neoplasms
- Connective Tissue Diseases
- Coronary Artery Disease
- Coronary Disease
- Coronary Restenosis
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Fetal Diseases
- Genetic Predisposition to Disease