ALDH2 (Human) Recombinant Protein (P01)
产品名称： ALDH2 (Human) Recombinant Protein (P01)
英文名称： ALDH2 (Human) Recombinant Protein (P01)
产品编号： H00000217-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human ALDH2 full-length ORF ( NP_000681.2, 1 a.a. - 517 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS
- Theoretical MW (kDa):
- 82.8
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 217
- GeneBank Accession#:
- NM_000690.2
- Protein Accession#:
- NP_000681.2
- Gene Name:
- ALDH2
- Gene Alias:
- ALDH-E2,ALDHI,ALDM,MGC1806
- Gene Description:
- aldehyde dehydrogenase 2 family (mitochondrial)
- Omim ID:
- 100650
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq
- Other Designations:
- ALDH class 2,acetaldehyde dehydrogenase 2,liver mitochondrial ALDH,mitochondrial aldehyde dehydrogenase 2,nucleus-encoded mitochondrial aldehyde dehydrogenase 2
- Gene Pathway
- 3-Chloroacrylic acid degradation
- Arginine and proline metabolism
- Ascorbate and aldarate metabolism
- beta-Alanine metabolism
- Butanoate metabolism
- Fatty acid metabolism
- Glycerolipid metabolism
- Glycolysis / Gluconeogenesis
- Histidine metabolism
- Limonene and pinene degradation
- Lysine degradation
- Metabolic pathways
- Propanoate metabolism
- Pyruvate metabolism
- Tryptophan metabolism
- Valine, leucine and isoleucine degradation
- Related Disease
- Acute Disease
- Adenocarcinoma
- Adenoma
- Adenomatous Polyps
- Alcohol Withdrawal Delirium
- Alcoholic Intoxication
- Alcoholic Neuropathy
- Alcoholism
- Alcohol-Related Disorders
- Alzheimer Disease
- Alzheimer disease
- Angina Pectoris
- Antisocial Personality Disorder
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Atrophy
- Attention Deficit Disorder with Hyperactivity