KCC2/SLC12A5-Specific 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
KCC2/SLC12A5-Specific 抗体

KCC2/SLC12A5-Specific 抗体

商家询价

产品名称： KCC2/SLC12A5-Specific 抗体

英文名称： KCC2/SLC12A5-Specific Antibody

产品编号： XY19565-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 KCC2/SLC12A5-SPECIFIC 抗体

Applications
In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
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  • 19565-1-AP;human brain tissuehuman brain tissue were subjected to SDS PAGE followed by western blot with 19565-1-AP(SLC12A5-Specific antibody) at dilution of 1:300
  • 19565-1-AP;H-brainImmunohistochemical of paraffin-embedded human brain using 19565-1-AP(SLC12A5-Specific antibody) at dilution of 1:100 (under 10x lens)
  • 19565-1-AP;H-brainImmunohistochemical of paraffin-embedded human brain using 19565-1-AP(SLC12A5-Specific antibody) at dilution of 1:100 (under 40x lens)
Positive WB detected in Human brain tissue, rat brain tissue
Positive IHC detected in Human brain tissue
Recommended dilution WB : 1:500-1:5000
IHC : 1:20-1:200
 KCC2/SLC12A5-SPECIFIC 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information KCC2/SLC12A5-SPECIFIC 抗体
Immunogen Peptide Full name Solute carrier family 12 (potassium-chloride transporter), member 5
Calculated molecular
weight		 126 kDa Observed molecular 
weight		 126 kDa
GenBank accession 
number		 NM_020708 Gene ID (NCBI) 57468
Gene symbol SLC12A5 Synonyms HKCC2, K Cl cotransporter 2, KCC2, KIAA1176, Neuronal K Cl cotransporter, SLC12A5
Background

KCC2, encoded by SLC12A5, is a neuron-specific K+-Cl- cotransporter that is essential for Cl- homeostasis and inhibitory synaptic transmission in brain. KCC2 is expressed at high levels in neurons throughout the nervous system. KCC2 deletion caused animal death. Alterations of KCC2 have been linked to neuropathic pain, temporal lobe epilepsy, and other diseases. This antibody can detect ~130 kda monomer and ~250 kDa dimer of KKC2 in brain lysate. (23401525) KCC2/SLC12A5-SPECIFIC 抗体

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