UBE3A/CEN15q FISH Probe-核酸检测-试剂-生物在线
亚诺法生技股份有限公司（Abnova)
UBE3A/CEN15q FISH Probe

UBE3A/CEN15q FISH Probe

商家询价

产品名称： UBE3A/CEN15q FISH Probe

英文名称： UBE3A/CEN15q FISH Probe

产品编号： FG0025

产品价格： 0

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围： null

亚诺法生技股份有限公司（Abnova)
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  • 邮编 : 11493
  • 所在区域 : 台湾
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  • 邮箱 : sales@abnova.com.tw
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  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FG0025
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Note:

  • Hybridization position of the probes on the chromosome.

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • UBE3A
    Approximately 370kb
    Texas Red
    15q11.2
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • CEN15q
    Approximately 680kb
    FITC
    15q11.2
  • Probe Gap:
  • The gap between two probes is approximately 5,700 kb.
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human breast cancer (FFPE) stained with UBE3A/CEN15q FISH Probe. Human breast cancer showed no UBE3A gene amplification
  • Protocol Download
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7337
  • Gene Name:
  • UBE3A
  • Gene Alias:
  • ANCR,AS,E6-AP,EPVE6AP,FLJ26981,HPVE6A
  • Gene Description:
  • ubiquitin protein ligase E3A
  • Gene Summary:
  • This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq
  • Other Designations:
  • CTCL tumor antigen se37-2,human papilloma virus E6-associated protein,oncogenic protein-associated protein E6-AP

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