FITC标记的电子转移黄素蛋白β肽/黄素蛋白抗体
产品名称： FITC标记的电子转移黄素蛋白β肽/黄素蛋白抗体
英文名称： Anti-ETFB/FITC
产品编号： HZ-3937R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-ETFB/FITC Conjugated antibody
FITC标记的电子转移黄素蛋白β肽/黄素蛋白抗体
| 英文名称 | Anti-ETFB/FITC |
| 中文名称 | FITC标记的电子转移黄素蛋白β肽/黄素蛋白抗体 |
| 别 名 | Flavoprotein; Beta ETF; FP; Beta-ETF; Electron transfer flavoprotein beta polypeptide; Electron transfer flavoprotein beta subunit; Electron transfer flavoprotein subunit beta; Electron transferring flavoprotein beta polypeptide; etfB; ETFB_HUMAN; FP585; MADD. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 转录调节因子 线粒体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 28kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ETFB |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase. Function: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Subunit: Heterodimer of an alpha and a beta subunit. Subcellular Location: Mitochondrion matrix. Tissue Specificity: Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas. DISEASE: Defects in ETFB are the cause of glutaric aciduria type 2B (GA2B) [MIM:231680]. GA2B is an autosomal recessively inherited disorder of fatty acid, amino acid, and choline metabolism. It is characterized by multiple acyl-CoA dehydrogenase deficiencies resulting in large excretion not only of glutaric acid, but also of lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Similarity: Belongs to the ETF beta-subunit/fixA family. Database links: UniProtKB/Swiss-Prot: P38117.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 黄素蛋白是由一条多肽结合1个辅基组成的酶类，不是脂溶性。结合的辅基可以是FAD或FMN,它们是维生素B2的衍生物，每个辅基能够接受和提供两个质子和电子。线粒体中的黄素蛋白主要是电子传递链中NADH脱氢酶和TCA循环中的琥珀酸脱氢酶 |
电子转移黄素蛋白作为几种脱氢酶的特异性电子受体，包括五酰基辅酶A脱氢酶、glutaryl CoA和肌氨酸脱氢酶。它通过ETF-泛醌氧化还原酶将电子传递到线粒体呼吸链的主要部分。