IL-6 (mouse):Fc (mouse) (rec.)(non-lytic)
产品名称: IL-6 (mouse):Fc (mouse) (rec.)(non-lytic)
英文名称:
产品编号: CHI-MF-12006
产品价格: 0
产品产地: USA
品牌商标: chimerigen
更新时间: null
使用范围: null
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Synonyms : Interleukin-6; B Cell Hybridoma Growth Factor; Interleukin HP-1 Host : CHO cell Sequence : The extracellular domain of mouse IL-6 (NP_112445.1)(Met1-Thr211) is fused to the N-terminus of the Fc portion of a mutant mouse IgG2a. Molecular Mass : 51KDa Non-lytic : Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement(C1q) and FcgRI binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity(ADCC) and complement directed cytotoxicity (CDC). Purity : ≥98%,by SDS-PAGE under reducing conditions. Endotoxin Content : <0.06 EU/μg as determined by LAL test. Activity : Measured by the dose-dependent stimulation of the proliferation of IL-6 dependent mouse 7TD1 cells Formulation : Lyophilized from 0.2μm-filtered solution in PBS. Reconstitution : Reconstitute at 100μg/ml in sterile PBS. Use / Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. Avoid freeze/thaw cycles.