Collagen TypeⅠ
胶原蛋白Ⅰ型

产品编号        规格      价格
C8060-1          1g       440.00

说明: 可作为胶原酶的底物。Ⅰ型胶原蛋白是皮肤、骨骼、肌腱以及其他纤维连接组织的组成成分。

别名：Collagen from bovine achilles tendon

CAS＃：9007-34-5

外观：乳白色纤维状

溶解性：不溶于水，水溶液，有机溶剂。

储存条件：2-8℃

Product Description ：
       This product is suitable for use as a substrate for collagenase. It is prepared by modification of the method of Einbinder and Schubert and is not suitable for use in coating glassware. 
This collagen is Bornstein and Traub Type I. The Type I classification of collagen is a component of skin, bone, tendon, and other fibrous connective tissues.  Type I collagen differs from other collagens by their low lysine hydroxylation and low carbohydrate composition. 
       Collagen breaks down metabolically in the body to release N-telopeptide, which is the N-terminus of collagen.  There is also C-telopeptide, which is presumably the C-terminus.  N-telopeptide is released in urine, and its detection in diagnostic tests is used to screen for osteoporosis. 
        Although different types of collagen exist, they are all composed of molecules containing three polypeptide chains arranged in a triple helical conformation.  Slight differences in the primary structure (amino acid sequence) establish differences between the types.  The amino acid sequence of the primary structure is mainly a repeating motif with glycine in every third position and proline or 4-hydroxyproline frequently preceeding the glycine residue. 
Preparation Instructions 
       This product is an insoluble collagen preparation. It is insoluble in water, aqueous buffers, dilute acid, and organic solvents. For use as a substrate in collagenase assays, this collagen can be prepared as a suspension in 50 mM TES buffer, pH 7.4 with 0.36 mM calcium chloride. but not a clear solution. 
Storage/Stability 
      It is recommended to store this product at 2–8 °C. If stored as recommended, it will have a shelf-life of up to 8 years. 
Precautions and Disclaimer 
      For Laboratory Use Only. Not for drug, household or other uses.