JPH3 polyclonal antibody
产品名称： JPH3 polyclonal antibody
英文名称： JPH3 polyclonal antibody
产品编号： PAB16594
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of JPH3.
- Immunogen:
- A synthetic peptide corresponding to C-terminus 18 amino acids of human JPH3.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.
Kakizawa S, Kishimoto Y, Hashimoto K, Miyazaki T, Furutani K, Shimizu H, Fukaya M, Nishi M, Sakagami H, Ikeda A, Kondo H, Kano M, Watanabe M, Iino M, Takeshima H.EMBO J. 2007 Apr 4;26(7):1924-33. Epub 2007 Mar 8.
- 2.
- Functional uncoupling between Ca2+ release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilins.
Moriguchi S, Nishi M, Komazaki S, Sakagami H, Miyazaki T, Masumiya H, Saito SY, Watanabe M, Kondo H, Yawo H, Fukunaga K, Takeshima H.Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10811-6. Epub 2006 Jun 29.
- 3.
- Coexpression of junctophilin type 3 and type 4 in brain.
Nishi M, Sakagami H, Komazaki S, Kondo H, Takeshima H.Brain Res Mol Brain Res. 2003 Oct 21;118(1-2):102-10.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of JPH3 in Daudi cell lysate with JPH3 polyclonal antibody (Cat # PAB16594) at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
- Entrez GeneID:
- 57338
- Protein Accession#:
- NP_065706
- Gene Name:
- JPH3
- Gene Alias:
- CAGL237,FLJ44707,HDL2,JP-3,JP3,TNRC22
- Gene Description:
- junctophilin 3
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family. [provided by RefSeq
- Other Designations:
- junctophilin type 3,trinucleotide repeat containing 22
- Related Disease