FITC标记的环磷酸腺苷调节元件相关蛋白1抗体
产品名称： FITC标记的环磷酸腺苷调节元件相关蛋白1抗体
英文名称： Anti-CROP/FITC
产品编号： HZ-14067R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-CROP/FITC Conjugated antibody
FITC标记的环磷酸腺苷调节元件相关蛋白1抗体
| 英文名称 | Anti-CROP/FITC |
| 中文名称 | FITC标记的环磷酸腺苷调节元件相关蛋白1抗体 |
| 别 名 | cAMP regulatory element-associated protein 1; Cisplatin resistance-associated overexpressed protein; Cisplatin resistance-associated-overexpressed protein; CRE-associated protein 1; CREAP-1; CREAP1; CROP; LC7L3_HUMAN; Luc7-like protein 3; Luc7A; LUC7L3; O48; Okadaic acid-inducible phosphoprotein OA48-18. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 51kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CROP |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2009] Function: Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. Subcellular Location: Nucleus speckle. The subnuclear localization is affected by cisplatin. Tissue Specificity: Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in fetal tissues, including brain, heart, kidney, thymus and lung. Post-translational modifications: Phosphorylated in vitro by SRPK1, SRPK2 and CLK1. Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the Luc7 family. Database links: Entrez Gene: 51747 Human Entrez Gene: 67684 Mouse Entrez Gene: 360602 Rat Omim: 609434 Human SwissProt: O95232 Human SwissProt: Q5SUF2 Mouse Unigene: 130293 Human Unigene: 30927 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码含有半胱氨酸/组氨酸基序和亮氨酸拉链样重复序列的N端半胱氨酸蛋白，C端半胱氨酸和谷氨酸残基(RE结构域)以及精氨酸和丝氨酸残基(RS结构域)丰富。该蛋白定位于细胞核内的斑点状结构，可能通过RE和RS结构域参与拼接体的形成。对该基因已发现编码相同蛋白质的两个交替剪接转录变体。[ RefSeq，Aug 2009提供]