FITC标记的半椎蛋白2抗体
产品名称： FITC标记的半椎蛋白2抗体
英文名称： Anti-HMCN2/FITC
产品编号： HZ-18048R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-HMCN2/FITC Conjugated antibody
FITC标记的半椎蛋白2抗体
| 英文名称 | Anti-HMCN2/FITC |
| 中文名称 | FITC标记的半椎蛋白2抗体 |
| 别 名 | Hemicentin 2 |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Dog, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 540kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HMCN2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: First discovered in C. elegans, Hemicentins are extracellular matrix (ECM) proteins that contain a single von Willebrand A domain at the amino terminus, more than 40 tandem immunoglobulin domains, multiple tandem epidermal growth factors, and a single fibulin-like carboxy-terminal module. In mammals, Hemicentins are expressed in the ECM of eye, skin and tongue epithelium and in the ECM of some blood vessels. Due to the expression pattern in areas that are subject to a significant amount of stress, it is thought that Hemicentins likely play a role in the architecture of flexible and adhesive cell junctions. Hemicentin-2 is a 5,065 amino acid secreted protein that is expressed in the extracellular matrix. There are three isoforms of Hemicentin-2 that are produced as a result of alternative splicing events Subcellular Location: Secreted Similarity: Contains 5 EGF-like domains. Contains 42 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 nidogen G2 beta-barrel domain. Contains 1 VWFA domain. Database links: Entrez Gene: 256158 Human SwissProt: Q8NDA2 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
首先在秀丽隐杆线虫中发现的半胱氨酸是细胞外基质（ECM）蛋白，在氨基末端含有单个von Willebrand A结构域、超过40个串联免疫球蛋白结构域、多个串联表皮生长因子和单个纤维蛋白样羧基末端模块。在哺乳动物中，半纤维素在眼睛、皮肤和舌头上皮的ECM和一些血管的ECM中表达。由于半胱氨酸在大量应激区域的表达模式，人们认为半胱氨酸可能在柔性和粘附性细胞连接的结构中发挥作用。半纤维素酶-2是在细胞外基质中表达的5065氨基酸分泌蛋白。有三种异构体的半纤维素酶-2是由于选择性剪接事件产生的。