Uniprot ID:Q96Q83
Species Reactivity:Human
Antibody type:Polyclonal Antibody
Aliases:Alkylated DNA repair protein alkB homolog 3,DEPC-1,Prostate cancer antigen 1,ABH3, DEPC1,ALKBH3Raised in:Rabbit
Background\Function :Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
Stroage Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purity:Caprylic Acid Ammonium Sulfate Precipitation purified
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