FITC标记的FUS2蛋白抗体
产品名称： FITC标记的FUS2蛋白抗体
英文名称： Anti-FUS2/FITC
产品编号： HZ-16196R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-FUS2/FITC Conjugated antibody
FITC标记的FUS2蛋白抗体
| 英文名称 | Anti-FUS2/FITC |
| 中文名称 | FITC标记的FUS2蛋白抗体 |
| 别 名 | AI225910; FUS 2; N acetyltransferase 6; NAT6; NAT6_HUMAN; OTTMUSP00000046403; OTTMUSP00000046404; OTTMUSP00000046405; OTTMUSP00000046406; Protein fus 2; Protein fusion 2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FUS2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring acetyl groups from acetyl CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located in the tumor suppressor gene region on chromosome 3p21.3 and the encoded protein may play a role in cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011] Function: FUS2 seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn. May act as a tumor suppressor. It is strongly expressed in heart and skeletal muscle, followed by brain and pancreas, with weak expression in kidney, liver, and lung and no expression in placenta. Defects in FUS2 are found in non-small cell lung cancer (NSCLC) cell lines. Subcellular Location: Cytoplasmic Tissue Specificity: Strongly expressed in heart and skeletal muscle, followed by brain and pancreas, with weak expression in kidney, liver, and lung and no expression in placenta. Similarity: Belongs to the acetyltransferase family. Contains 1 N-acetyltransferase domain. Database links: Entrez Gene: 24142 Human Omim: 607073 Human SwissProt: Q93015 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码N-乙酰转移酶家族的成员。N-乙酰转移酶通过将乙酰基从乙酰辅酶A转移到蛋白质底物的N-末端来修饰蛋白质。编码的蛋白质是具有N-末端蛋氨酸的蛋白质的底物特异性的细胞质N-乙酰转移酶。该基因位于3p1.3染色体上的肿瘤抑制基因区域，编码的蛋白可能在肿瘤中发挥作用。另外，已经观察到编码多个异构体的剪接转录变体。该基因与透明质糖氨基苷酶3重叠，并且位于同一条链上，并且每个基因的一些转录本共享第一外显子的一部分。[ RefSeq，2011月1日]