CLK1 polyclonal antibody
产品名称: CLK1 polyclonal antibody
英文名称: CLK1 polyclonal antibody
产品编号: PAB2924
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CLK1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CLK1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Regulation and substrate specificity of the SR protein kinase Clk/Sty.
Prasad J, Manley JL.Mol Cell Biol. 2003 Jun;23(12):4139-49.
- 2.
- Chromosomal mapping of three human LAMMER protein-kinase-encoding genes.
Talmadge CB, Finkernagel S, Sumegi J, Sciorra L, Rabinow L.Hum Genet. 1998 Oct;103(4):523-4.
- 3.
- Characterization by cDNA cloning of two new human protein kinases. Evidence by sequence comparison of a new family of mammalian protein kinases.
Hanes J, von der Kammer H, Klaudiny J, Scheit KH.J Mol Biol. 1994 Dec 16;244(5):665-72.
- Entrez GeneID:
- 1195
- Protein Accession#:
- CLK1_HUMAN
- Gene Name:
- CLK1
- Gene Alias:
- CLK,CLK/STY,STY
- Gene Description:
- CDC-like kinase 1
- Omim ID:
- 601951
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CDC28/CDC2-like kinase,dual specificity protein kinase CLK1,protein tyrosine kinase STY