FBXL17,FBXL17蛋白抗体

产品编号HZ-8469R
英文名称FBXL17
中文名称FBXL17蛋白抗体
别 名F box and leucine rich repeat protein 17; F box only protein 13; F box/LRR repeat protein 17; F-box and leucine-rich repeat protein 17; F-box only protein 13; F-box/LRR-repeat protein 17; FBL17; FBX13; Fbxl17; FBXO13; FBXL13; FXL17_HUMAN; DKFZP434C1715.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 泛素
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
FBXL17,FBXL17蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量76kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human FBXL17
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
FBXL17,FBXL17蛋白抗体PubMedPubMed
产品介绍background:
Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Subunit:
Interacts with SKP1 and CUL1

Similarity:
Contains 1 F-box domain.

Database links:
Entrez Gene: 64839 Human
Entrez Gene: 50758 Mouse
Entrez Gene: 316663 Rat
Omim: 609083 Human
SwissProt: Q9UF56 Human
SwissProt: Q9QZN1 Mouse
Unigene: 657225 Human
Unigene: 721914 Human
Unigene: 136366 Mouse

FBXL17,FBXL17蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.