FITC标记的脑肠肽受体抗体
产品名称： FITC标记的脑肠肽受体抗体
英文名称： Anti-Ghrelin Receptor/FITC
产品编号： HZ-11529R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Ghrelin Receptor/FITC Conjugated antibody
FITC标记的脑肠肽受体抗体
| 产品编号 | bs-11529R-FITC |
| 英文名称 | Anti-Ghrelin Receptor/FITC |
| 中文名称 | FITC标记的脑肠肽受体抗体 |
| 别 名 | GH releasing peptide receptor; GH-releasing peptide receptor; Ghrelin receptor; GHRP; GHRPR; GHS-R; GHS-R1; GHSR; GHSR_HUMAN; Growth hormone secretagogue receptor 1; Growth hormone secretagogue receptor type 1; growth hormone secretatgogue receptor. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 神经生物学 信号转导 生长因子和激素 细胞膜受体 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Ghrelin Receptor (75-135aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the G-protein coupledreceptor family. The encoded protein may play a role in energyhomeostasis and regulation of body weight. Two identifiedtranscript variants are expressed in several tissues and areevolutionary conserved in fish and swine. One transcript, 1a,excises an intron and encodes the functional protein; this proteinis the receptor for the Ghrelin ligand and defines a neuroendocrinepathway for growth hormone release. The second transcript (1b)retains the intron and does not function as a receptor for Ghrelin;however, it may function to attenuate activity of isoform 1a.Mutations in this gene are associated with autosomal idiopathicshort stature.[provided by RefSeq, Apr 2010]. Function: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). Subcellular Location: Cell membrane. Tissue Specificity: Pituitary and hypothalamus. DISEASE: Defects in GHSR may be a cause of idiopathic short stature autosomal (ISSA) [MIM:604271]. Short stature is defined by a subnormal rate of growth. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 2693 Human Entrez Gene: 208188 Mouse Entrez Gene: 397372 Pig Entrez Gene: 84022 Rat Omim: 601898 Human SwissProt: Q6ISR8 Human SwissProt: Q92847 Human SwissProt: Q99P50 Mouse SwissProt: Q95254 Pig SwissProt: O08725 Rat Unigene: 130212 Human Unigene: 194721 Mouse Unigene: 16107 Pig Unigene: 74241 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码G蛋白偶联受体家族的一个成员。编码的蛋白质可能在能量平衡和体重调节中发挥作用。在鱼类和猪中，两种识别的转录变体在多种组织中表达，并且是进化保守的。一个转录物，1A，切除内含子并编码功能蛋白；该蛋白是Ghrelin配体的受体，并定义了生长激素释放的神经内分泌途径。第二转录物（1b）保留内含子，不起Ghrelin受体的作用；然而，它可能起到减弱亚型1A活性的作用。该基因的突变与常染色体特发性矮小症有关。[ RefSeq，APR 2010 ]提供。