Synonyms : Fc region of human immunoglobulin G1
Host : HEK293 cell line
Sequence : Mutant human IgG1 Fc region ,Pro100-Lys330 (Leu118Glu, Glu201Ala, Lys203Ala, Lys205Ala), containing the hinge sequence
Molecular Mass: 26 KDa (monomer)
Non-lytic: Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).
Purity : >98%，by SDS-PAGE under reducing conditions.
Endotoxin Content : <0.06 EU/μg as determined by LAL test.

Formulation : Lyophilized from 0.2μm-filtered solution in PBS.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Application Notes: This product should be used as the control protein in the activity test of chimeric protein of Human target protein and Human IgG-Fc domain.
Use / Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Avoid freeze/thaw cycles.