FITC标记的Nibp蛋白抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的Nibp蛋白抗体

FITC标记的Nibp蛋白抗体

商家询价

产品名称: FITC标记的Nibp蛋白抗体

英文名称: Anti-TRAPPC9/FITC

产品编号: HZ-16589R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-TRAPPC9/FITC Conjugated antibody

FITC标记的Nibp蛋白抗体

 

英文名称 Anti-TRAPPC9/FITC
中文名称 FITC标记的Nibp蛋白抗体
别    名 1810044A24Rik; 2900005P22Rik; 4632408O18Rik; Ibp; IKBKBBP; Ikk2 binding protein; KIAA1882; MGC4737; MGC4769; mKIAA1882; MRT13; Nibp; NIK and IKK(beta) binding protein; NIK and IKK{beta} binding protein; RGD1309461; T1; Trafficking protein particle complex 9; TPPC9_HUMAN; TRAPP 120 kDa subunit; TRS130; Tularik gene 1 protein.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  转运蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 128kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRAPPC9
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been associated with autosomal-recessive mental retardation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]

Function:
TRAPPC9 functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. It may also function in neuronal cells differentiation and play a role in vesicular transport from endoplasmic reticulum to Golgi.

Subunit:
Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12. Directly interacts with IKBKB and MAP3K14.

Subcellular Location:
Golgi apparatus; cis-Golgi network. Endoplasmic reticulum. Cytoplasm. Note: Processes and cell bodies of neurons.

Tissue Specificity:
Expressed at high levels in muscle and kidney and to a lower extent in brain, heart and placenta.

DISEASE:
Mental retardation, autosomal recessive 13 (MRT13) [MIM:613192]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Brain magnetic resonance imaging of MRT13 patients indicates the presence of mild cerebral white matter hypoplasia. Microcephaly is present in some but not all affected individuals. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the NIBP family.

Database links:

Entrez Gene: 83696 Human

Omim: 611966 Human

SwissProt: Q96Q05 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

该基因编码可能在NF-κB信号转导中起作用的蛋白质。该基因突变与常染色体隐性智力低下有关。另一种剪接转录变体已被描述。[由RefSeq,FEB 2010提供]