MTM1 polyclonal antibody
产品名称： MTM1 polyclonal antibody
英文名称： MTM1 polyclonal antibody
产品编号： PAB4507
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MTM1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MTM1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP.
Nandurkar HH, Layton M, Laporte J, Selan C, Corcoran L, Caldwell KK, Mochizuki Y, Majerus PW, Mitchell CA.Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8660-5. Epub 2003 Jul 7.
- 2.
- PTEN and myotubularin phosphatases: from 3-phosphoinositide dephosphorylation to disease.
Wishart MJ, Dixon JE.Trends Cell Biol. 2002 Dec;12(12):579-85.
- 3.
- Characterisation of mutations in 77 patients with X-linked myotubular myopathy, including a family with a very mild phenotype.
Biancalana V, Caron O, Gallati S, Baas F, Kress W, Novelli G, D'Apice MR, Lagier-Tourenne C, Buj-Bello A, Romero NB, Mandel JL.Hum Genet. 2003 Feb;112(2):135-42. Epub 2002 Nov 28.
- Entrez GeneID:
- 4534
- Protein Accession#:
- NP_000243;Q13496
- Gene Name:
- MTM1
- Gene Alias:
- CNM,MTMX,XLMTM
- Gene Description:
- myotubularin 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a dual-specificity phosphatase that acts on both phosphotyrosine and phosphoserine. It is required for muscle cell differentiation and mutations in this gene have been identified as being responsible for X-linked myotubular myopathy. [provided by RefSeq
- Other Designations:
- myotubularin
- Related Disease