BCL2L1 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： BCL2L1 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： BCL2L1 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00000598-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human BCL2L1 protein.
- Immunogen:
- BCL2L1 (NP_612815.1, 1 a.a. ~ 233 a.a) full-length human protein.
- Sequence:
- MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- BCL2L1 MaxPab rabbit polyclonal antibody. Western Blot analysis of BCL2L1 expression in human spleen.
- Protocol Download
- Western Blot (Cell lysate)
- BCL2L1 MaxPab rabbit polyclonal antibody. Western Blot analysis of BCL2L1 expression in A-431.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of BCL2L1 expression in transfected 293T cell line (H00000598-T01) by BCL2L1 MaxPab polyclonal antibody.
Lane 1: BCL2L1 transfected lysate(26.00 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- In situ Proximity Ligation Assay (Cell)
- Proximity Ligation Analysis of protein-protein interactions between BCL2L1 and BAX. HeLa cells were stained with anti-BCL2L1 rabbit purified polyclonal 1:1200 and anti-BAX mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
- Entrez GeneID:
- 598
- GeneBank Accession#:
- NM_138578
- Protein Accession#:
- NP_612815.1
- Gene Name:
- BCL2L1
- Gene Alias:
- BCL-XL/S,BCL2L,BCLX,Bcl-X,DKFZp781P2092,bcl-xL,bcl-xS
- Gene Description:
- BCL2-like 1
- Omim ID:
- 600039
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq
- Other Designations:
- OTTHUMP00000030550,OTTHUMP00000030551,OTTHUMP00000030553
- Interactome
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Amnesia
- Cognition Disorders
- Colorectal Neoplasms
- Disease Progression
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hodgkin Disease
- Lymphoma, B-Cell
- Lymphoma, Follicular
- Lymphoma, Large B-Cell, Diffuse
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Multiple Sclerosis
- Neoplasm Metastasis
- Neuropsychological Tests
- Occupational Diseases