阿拉丁小分子抑制剂、激动剂、拮抗剂--G蛋白偶联受体信号通路（下）-自主发布-资讯-生物在线
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阿拉丁小分子抑制剂、激动剂、拮抗剂--G蛋白偶联受体信号通路（下）

作者：上海阿拉丁生化科技股份有限公司 2020-07-10T17:08 (访问量:4162)

style="vertical-align: top; padding: 0px; box-sizing: border-box;"> P129443Pramipexole 2HCl Monohydrate≥98%(HPLC)191217-81-950mg,250mg,1gD2S受体3.9 nM D2L受体2.2 nM D3受体0.5 nM D4受体5.1 nM P129434Pramipexole≥99%104632-26-010mg,50mgD2S受体3.9 nM D2L受体2.2 nM D3受体0.5 nM D4受体5.1 nM D103111盐酸多巴胺98%62-31-75g,25g,100g,500g,2.5kg多巴胺受体 P129456Pergolide mesylate≥99%66104-23-22.5mg B178171brexpiprazole97%913611-97-91gD2L0.3 nM5-HT1A0.12 nM5-HT2A0.47 nMα1B受体0.17 nMα2C受体0.59 nMP160771吡贝地尔>98.0%(GC)(T)3605-01-4200mg,1gP129442PD128907 HCl≥98%112960-16-45mg,25mg,100mg多巴胺D3受体 0.64 nMR126364Rotigotine≥98%99755-59-610mg,50mg多巴胺受体P165634Pramipexole dihydrochloride>98% (HPLC)104632-25-910mg,50mgD2S受体3.9 nMD2L受体2.2 nMD3受体0.5 nMD4受体5.1 nMM132847MPTP盐酸盐≥98%23007-85-425mg,100mgO101521章胺盐酸盐98%770-05-81g,5g

*阿片受体

项目号产品名称规格CAS包装靶点IC50Ki
R126180Racecadotril≥98%81110-73-8250mg,1g,5g,25g阿片受体4.5 μM
N129470Naloxone HCl≥99%357-08-450mg,250mg,1g
J125889JTC-801≥99%244218-51-75mg,10mg,50mgORL194 nM
N129461Naltrexone HCl≥99%16676-29-250mg,250mg,1g阿片受体8 nM
A124975Alvimopan≥98%156053-89-325mg,100mgμ阿片受体0.77 nM
δ阿片受体4.4 nM
κ阿片受体40 nM
L129465Loperamide HCl≥98%34552-83-55g,25gμ阿片受体3.3 nM
δ阿片受体48 nM
A127848ADL5859 HCl≥98%850173-95-41mg,5mg,10mg,50mgδ阿片受体0.8 nM
M109803苦参碱98%519-02-8100mg,1g,5g,25gκ阿片受体
M109802苦参碱分析标准品,≥98%519-02-820mgκ阿片受体
T129468Trimebutine≥98%39133-31-8250mg,5g,25g,100gμ阿片受体
δ阿片受体
κ阿片受体
M129400Meptazinol HCl≥99%59263-76-210mg,50mg,250mg阿片受体

*大麻素受体

项目号产品名称规格CAS包装靶点IC50KiEC50
O135157橄榄醇95%500-66-31g,5g
R125003Rimonabant≥98%168273-06-110mg,50mg,500mghCB113.6 nM
A129844AM251≥98%183232-66-85mg,25mg,100mgCB1 700 nM
C129834CP-945598 HCl≥98%686347-12-610mg,50mgCB10.7 nM
A129838AM1241≥98%444912-48-55mg,10mg,25mg,50mgCB23.4 nM
B126713BML-190≥99%2854-32-210mg,50mgCB2435 nM
G129840GW842166X≥98%666260-75-95mg,25mg,100mgCB263 nM
O129837Org 27569≥98%868273-06-710mg,50mgCB1

*内皮素受体

项目号产品名称规格CAS包装靶点IC50
Z125040Zibotentan (ZD4054)≥98%186497-07-45mg,25mg,100mgET-A21 nM
B129849Bosentan Hydrate≥99%157212-55-050mg,250mg,1g,5gET-A4.7 nM
ET-B95 nM
M125524Macitentan≥97%441798-33-05mg,25mg,100mg,1gET-A0.5 nM
ET-B391 nM
A126631Ambrisentan≥99%177036-94-15mg,10mg,20mg,100mg,250mg,1gET-A18 nM

*S1P受体

项目号产品名称规格CAS包装细胞靶点IC50KiEC50
S129855SKI II≥98%312636-16-15mg,25mg,100mg SphK0.5 μM
P125702PF-543-1415562-82-15mg,10mg,50mg SphK13.6 nM
A127517ABC294640≥99% 915385-81-85mg,10mg,50mg SphK260 μM
F126599Fingolimod HCl≥98%162359-56-0100mg,200mg,250mg,1gK562 、NK细胞S1P0.33 nM
P177659Ponesimod97%854107-55-4100mgS1P15.7 nM

*Hedgehog/Smoothened

项目号产品名称规格CAS包装细胞靶点IC50KiKd
V127477Vismodegib (GDC-0449)98%879085-55-910mg,50mg,100mg,250mg,500mg,1g无细胞hedgehog3 nM
L125247LY2940680≥99%1258861-20-95mg,10mg,50mg Smo
J169510JK18498% (HPLC)315703-52-75mg,25mg哺乳动物细胞Gli30 nM
J135916Jervine>97.0%(HPLC)469-59-010mg,25mg,50mg,100mg,250mg Hedgehog500-700 nM
C125994Cyclopamine≥99%4449-51-85mg,10mg,50mgTM3Hh12细胞Smo46 nM
L127562NVP-LDE225≥99%956697-53-310mg,50mg,100mg无细胞Smo (小鼠)1.3 nM
无细胞Smo (人) 2.5 nM
P126554PF-5274857≥99%1373615-35-05mg,10mg,50mg Smo5.8 nM4.6 nM
S129830SANT-1≥98%304909-07-75mg,25mg,100mg Smo1.2 nM
B126389BMS-833923≥99%1059734-66-510mg,50mgSmo
P1260
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