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上海信裕生物科技有限公司
NSUN2抗体

NSUN2抗体

商家询价

产品名称： NSUN2抗体

英文名称： NSUN2Antibody

产品编号： XY20854-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 NSUN2抗体Applications

In-house applications ELISA, IHC, IF, IP, WB     Application not tested? Please see our Guarantee.
Published applications IF, IP, WB Publications 6 citations –view here
Species specificity Human, Mouse; other species not tested.
Published Species Human, mouse
Images
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  • 20854-1-AP;HEK-293WB result of NSUN2 antibody (20854-1-AP, 1:5000) with si-Control and si-NSUN2 transfected HepG2 cells.
  • 20854-1-AP;human breast cancerImmunohistochemical of paraffin-embedded human breast cancer using 20854-1-AP(NSUN2 antibody) at dilution of 1:100 (under 10x lens)
  • 20854-1-AP;human breast cancerImmunohistochemical of paraffin-embedded human breast cancer using 20854-1-AP(NSUN2 antibody) at dilution of 1:100 (under 40x lens)
  • 20854-1-AP;HelaImmunofluorescent analysis of Hela cells, using NSUN2 antibody 20854-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
  • 20854-1-AP;HeLa cellsIP Result of anti-NSUN2 (IP:20854-1-AP, 4ug; Detection:20854-1-AP 1:1000) with HeLa cells lysate 4000ug.
Positive WB detected in HEK-293, COLO 320 cells, HeLa cells, HepG2 cells, MCF7 cells, SH-SY5Y cells
Positive IP detected in HeLa cells
Positive IHC detected in Human breast cancer tissue, human testis tissue
Positive IF detected in Hela cells, HepG2 cells
Recommended dilution WB : N/A
IP : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:10-1:100
 NSUN2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information NSUN2抗体
Immunogen NSUN2 fusion protein ag14791 Full name NOL1/NOP2/Sun domain family, member 2
Calculated molecular
weight		 767aa,86 kDa Observed molecular 
weight		 90-100 kDa
GenBank accession 
number		 BC001041 Gene ID (NCBI) 54888
Gene symbol NSUN2 Synonyms FLJ20303, hTrm4, MISU, NSUN2, SAKI, TRM4
Background

NSUN2, also known as SAKI or Misu (Myc-induced SUN-domain-containing protein) , is a methyltransferase which catalyses (cytosine-5-)-methylation of tRNA. NSUN2 is direct target gene of c-Myc and may act downstream of Myc to regulate epidermal cell growth and proliferation. NSUN2 is overexpressed in various cancer tissues and may be a valuable target for cancer therapy and a cancer diagnostic marker. Recently a splicing mutation in NSUN2 has been identified as the cause of a Dubowitz-like syndrome, an autosomal recessive disorder. NSUN2抗体

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