Pre-IL18抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
Pre-IL18抗体

Pre-IL18抗体

商家询价

产品名称: Pre-IL18抗体

英文名称: Pre-IL18Antibody

产品编号: XY 10663-1-

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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  • 邮编 : 200612
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 PRE-IL18抗体Applications

In-house applications ELISA, WB, IP, IHC, IF     Application not tested? Please see our Guarantee.
Published applications IHC, WB Publications 2 citations –view here
Species specificity Human; other species not tested.
Published Species Human, mouse
Images
Prev12NextView more validation data
  • 10663-1-AP;HeLa cellsHeLa cells were subjected to SDS PAGE followed by western blot with 10663-1-AP(Pre-IL18 antibody) at dilution of 1:1000
  • 10663-1-AP;HeLa cellsIP Result of anti-Pre-IL18 (IP:10663-1-AP, 3ug; Detection:10663-1-AP 1:1000) with HeLa cells lysate 5000ug.
  • 10663-1-AP;human tonsillitis tissueImmunohistochemical of paraffin-embedded human tonsillitis using 10663-1-AP(Pre-IL18 antibody) at dilution of 1:50 (under 10x lens)
  • 10663-1-AP;human tonsillitis tissueImmunohistochemical of paraffin-embedded human tonsillitis using 10663-1-AP(Pre-IL18 antibody) at dilution of 1:50 (under 40x lens)
  • 10663-1-AP;Transfected HEK-293 cellsTransfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 10663-1-AP( Pre-IL18 Antibody) at dilution of 1:1000
  • 10663-1-AP;HeLa cellsImmunofluorescent analysis of HeLa cells using 10663-1-AP( Pre-IL18 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in HeLa cells, Transfected HEK-293 cells
Positive IP detected in HeLa cells
Positive IHC detected in Human tonsillitis tissue, human colon cancer tissue
Positive IF detected in HeLa cells
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:10-1:100
PRE-IL18抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen InformationPRE-IL18抗体
Immunogen Pre-IL18 fusion protein ag1063 Full name Interleukin 18 (interferon-gamma-inducing factor)
Calculated molecular
weight
193aa,22 kDa Observed molecular 
weight
18-24 kDa
GenBank accession 
number
BC007461 Gene ID (NCBI) 3606
Gene symbol IL18 Synonyms Iboctadekin, IFN gamma inducing factor, IGIF, IL 1 gamma, IL 18, IL 1g, IL18, IL1F4, Interleukin 1 gamma, Interleukin 18, Mature IL18, pre IL18
Background

IL18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release interferon gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 24 kDa precursor and then cleaved into a biologically activate 18 kDa form. This antibody 10663-1-AP is raised against the full length IL18 precursor, and it recognizes both the pre-IL18 and mature IL18PRE-IL18抗体 theoretically.

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