Does NKG2D play a role in your research?

来源: BioXcell   2020-7-3   访问量:1756评论(0)

The World's #1 Supplier for in vivo-ready Antibodies

InVivoMAb anti-mouse NKG2D (CD314)

CLONE CX5

The CX5 monoclonal antibody reacts with mouse NKG2D, a type II transmembrane lectin-like glycoprotein also known as CD314. NKG2D is expressed on NK cells, NKT cells, CD8 T cells, γ/δ T cells, and macrophages. NKG2D has been implicated in anti-tumor surveillance, the immune response against viral infection, and in diabetes progression in NOD mice. Previous studies have shown that CX5 is a non-depleting antibody, which blocks binding of NKG2D to its ligands and mediates internalization of the receptor.



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